Ameloblastic carcinoma is a rare form of odontogenic tumor, one that develops in the jawbones from the epithelial cells that generate the tooth enamel. Mandible / maxilla – Malignant tumors: ameloblastic carcinoma. Ameloblastic carcinoma is a rare odontogenic malignancy that combines the histological features of ameloblastoma with cytological atypia.

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Devenney-Cakir et al [ 13 ]. Wide surgical excision provides the best chance of controlling the tumor. The two such forms include malignant ameloblastoma, and ameloblastic carcinoma. Different forms of cancer, including odontogenic tumors, are classified based upon the cell type involved, the specific nature of the malignancy, and the disease’s clinical course.

Received Mar 5; Accepted Dec carcinooma Malignant variants of the ameloblastoma are exceptionally rare and may arise de novo or from transformation of a long-standing primarily benign lesion which has undergone several surgical excision [ 5 ]. It may present as a cystic lesion with benign clinical features or as a large tissue mass with ulceration, significant bone resorption and tooth mobility.

Ameloblastic Carcinoma

Rare diseases, including the ameloblastoma to ameloblastic carcinoma spectrum, require randomized multicenter studies in order to define novel and improved treatments. Otolaryngol Head Neck Surg. J Can Dent Assoc.

Observations on the origin of the granular cells. Investigational Therapies Information on current clinical trials is posted on the Internet at www. Niger J Surg Res ;7: It is of interest that ameloblastic carcinoma can apparently arise from a cystic lining.

Rare localization of a rare neoplasm. In addition, rapid tumor ameloblashic may perforate the cortical bone and extend into the soft tissue, causing pain and paresthesia.

We report a series of six cases with our treatment modalities. As a relatively rare malignant tumor, further detailed and systematic studies regarding ameloblastic carcinoma are required. This article has been cited by 1 Reconnoitre ameloblastic carcinoma: Report of an aggressive case and review of the literature.


A year-old male was diagnosed with left jaw ameloblastoma. A relatively low-density signal was observed in catcinoma C3—C6 area. None of our patients were sent for radiotherapy or chemotherapy.

In carcijoma, few chemotherapy reports are available and its role is yet to be confirmed Maxillary ameloblastic carcinoma in a child. Primary intraosseous carcinoma of the jaws.

Ameloblastic carcinoma: An analysis of 12 cases with a review of the literature

Introduction Ameloblastic carcinoma is a relatively rare type of tumor. Radiological investigations include both the plain X-ray and computerized axial tomography. Surgical resection of the primary tumor with wide margins is the mainstay treatment of ameloblastic carcinoma. Oral and Maxillofacial Pathology, 3rd Edition, They may affect individuals of any age including children, but the mean age of affected individuals is approximately 30 years old. Wide local excision is the treatment of choice.

Ameloblastic carcinoma: A case series

J Dent Allied Sci ;6: While novel therapeutic regimens should also be considered as appropriate, including carbon ion therapy and Gamma Knife stereotactic radiosurgery. Angiero et al 5 argued that since metastases is able to occur via the blood stream, cervical lymph node dissection should not be routinely performed. Annals Dent Univ Malaya.

Introduction Ameloblastoma is a benign but locally aggressive odontogenic epithelial neoplasm, which presents as a slowly growing painless swelling of the jaws.

Symptoms may include progressive pain and swelling of the jaw. Br J Oral Maxillofac Surg ; In one reported case, the primary site was the anterior skull base. Ameloblastic carcinoma of the mandible resembling odontogenic cyst in a panoramic radiograph.

Abstract The maxilla is an unusual site for an ameloblastoma, and certainly for an ameloblastic carcinoma. The term carcinima refers to a group of diseases characterized by abnormal, uncontrolled cellular growth that invades surrounding tissues and may spread metastasize to distant bodily tissues or organs via the bloodstream, ameloboastic lymphatic system, or other means.


Ameloblastic carcinoma of the maxilla: Ion beam therapy, which delivers high doses to the target tumor while sparing the normal surrounding tissues, is a novel therapy for cancer. Discussion Ameloblastic carcinoma is a lesion with histologic behavior that dictates a more aggressive surgical approach than that of a simple ameloblastoma. J Maxillofac Oral Surg ;9: In total, 12 patients with ameloblastic carcinoma who were treated at the West China Hospital of Stomatology, Sichuan University Chengdu, China between and Table Iand 20 more cases reported between and identified by searching PubMed http: In this series, amelooblastic cases proved to be that of ameloblastic carcinoma.

Although we could not ascertain unequivocally whether ameloblastic carcinoma in our patient developed de novo carcinoja from a pre-existing ameloblastoma, we believe amepoblastic former might be the most likely due to the absence of any history of previously operated tumour from the site and the short duration of the lesion.

All patients had a Chest X-ray and an abdomen ameloblastuc done to avoid missing distant metastasis as we were aware of the potential of this lesion to metastasize. Radiotherapy in the treatment of ameloblastic carcinoma.

Case report and review of the literature. Treatment strategy of a huge ameloblastic carcinoma.

Ameloblastic Carcinoma – NORD (National Organization for Rare Disorders)

Jaw extended resection, neck dissection, radiation. Ameloblastic carcinoma ex ameloblastoma of the mandible with malignancy-associated hypercalcemia. Nil Conflict of Interest: